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Cannabis contains substances that affect the brain and body, including delta-9-tetrahydrocannabinol (THC) CBD and cannabidiol (CBD). The current National Institute for Health and Care Excellence (NICE) guidance for the pharmacological management of neuropathic pain suggests offering a choice of amitriptyline, duloxetine, gabapentin, or pregabalin as initial treatment for neuropathic pain (with the exception of trigeminal neuralgia), with switching if the first, second, or third drugs tried are not effective or not tolerated ( NICE 2013 ). This concurs with other recent guidelines ( Finnerup 2015 ). Their Relief Rub is a CBD topical balm made from multiple natural oils, with a mild minty fragrance.

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Often the confusion happens in the mis-labeling of Hemp Seed Oil, as Hemp Oil or even CBD Oil. One very broad study found that those with the highest levels of medical marijuana use had significantly lower levels of ALD at all stages of the disease. While most of these are classed as full-spectrum CBD oils (whole plant extracts) and contain trace levels of THC, there are many which contain 0.00% THC. The process of extracting CBD oil is unlikely to produce oil with high levels of THC, and CBD on its own doesn’t get you high.

  • However, phytocannabinoids—a.k.a. cannabinoid compounds that come from plants instead of the human body like endocannabinoids—as found in both CBD and THC products, can also react with the endocannabinoid system and affect how it runs.
  • As long as the CBD oil you use contains no more than 0.3% THC, it’s classified as a hemp product and is therefore legal.
  • With a new and improved 2018 Farm Bill on the table in the House for voting as we speak, the passing of which will clear up all confusion about industrial hemp, and lead to CBD products to be thoroughly tested by the FDA.

Unrefined hemp oil contains plant oils that dilute the strength of the CBD. Unlike opioids and other psychoactive treatments, CBD oil has virtually zero risks of overdosing. Further, a 1993 study conducted by pharmacology researchers at the University of California, San Francisco, and published in the journal Biochemical Pharmacology, discovered that CBD, much like grapefruit, disrupts the normal function of cytochrome P450 enzymes in mice. Unfortunately, some 100% legal CBD oil can lead to a positive drug test.

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Since the topical application of CBD takes the substance from the site of administration directly to the affected site it has the least risk of interacting with other drugs. But CBD, being an extract from hemp – a major component of cannabis – exhibits the unique property of interacting with the endocannabinoid system in the human body in a therapeutic manner. Their study confirmed that the rodents consumed less alcohol and drugs as a result of using CBD on a daily basis, and were able to tolerate anxiety-inducing situations” that could trigger a relapse.