CBD, or Cannabidiol, is a cannabinoid found within the cannabis plant. A non-psychoactive relative of cannabinoids such as THC and THC-N, CBD has been the subject of intense discussion and debate within the medical community as of late for its use as an anti-seizure medication. Popularized by carefully bred strains such as Charlotte’s Web and Harlequin, CBD oil is helping many to transition away from a diet of prescriptions and into an alternative style of medicine.
It feels condescending to suggest that, given there are hoards of people who love their CBD tinctures and gummies and claim effects from it. It’s a tremendously rude thing to say, hey, you’re all being hoodwinked. But the placebo effect is much stronger than you might think.
This is due to the amount of time it takes for the oil to absorb through the skin and start acting with the appropriate receptors. CBD oil is made from the hemp flower and stalks, which contains more significant levels of active cannabinoids.
However, you may not notice any specific results within the first day. Another popular chemical substance found in the marijuana (or cannabis) plant is Tetrahydrocannabinol (THC), which is the psychoactive cannabinoid that is responsible for the ‘stoned’ feeling when marijuana is taken. CBD though from the same plant does not give a feeling of being ‘high’ which is quality makes it dissimilar from THC and medically legalized in some states.
There is only ever mention of thc levels being regulated and zero law regulating cbd content. My DEA sources are not “low level.” My primary source was Barbara Carreno who is the spokesperson for the entire agency! She says hemp products, like lotions and hemp oil for face clothing and that sort of thing, are exempt from the Controlled Substances Act. CBD oil, therefore, is not legal, whether it comes from the hemp stalk or the leaves – it still comes from the same plant – an illegal plant!
So, while it may be legal to use CBD in a state like Colorado or Alaska, if an employer follows federal regulations, the standardization and quality of a CBD product matters. Because if there’s even a small percentage of THC in that product, then a drug test might come back positive. This is very important for cancer patients to understand, as many people think CBD oil is not a medicine.
Several animal studies also suggest that THC and CBD work synergistically. A 2019 paper published in Frontiers in Pharmacology investigated the effects of both cannabinoids on models of neuro-hyperactivity in zebrafish. A randomised, placebo-controlled study published in the Journal of Pain and Symptom Management demonstrates the synergistic power of THC and CBD among a group of patients.
However, 17 subjects dropped out, and the study was neither randomized nor controlled, and therefore is not included in Table 1. Other “minor phytocannabinoids” in cannabis may also contribute relevant activity (McPartland and Russo 2001). Cannabichromene (CBC) is the third most prevalent cannabinoid in cannabis, and is also anti-inflammatory (Wirth et al 1980), and analgesic, if weaker than THC (Davis and Hatoum 1983).